Leflunomide is a prodrug, it inhibits pyrimidine synthesis, reduces leucocyte adhesion and cell infiltration, it also stimulates tissue growth factor beta formation and reduce the amount of osteoclasts (increases bone density as there are no more cell to break bone down!).
S/e include allopecia, diarrhea, vomiting and is embryotoxic
Hope this helps!
i suggest your supposed to rub it on.
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