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Close to zero. Animal test answers two questions:
1. Does the drug show value in treating an syndrome with a similar machinery in humans?
2. How toxic is the drug?
These two question must be answered before the subsequent step in drug nouns: phase one human trials. In these trials, the drug is given to a group of about 100 stout humans to determine bioavailability, preliminary dosage estimates, and the most common side effects.
Are you asking the side effects to animals or the side effects to humans using animals?
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